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Potential Influence of Helminth Molecules on COVID-19 Pathology.
Siles-Lucas, Mar; González-Miguel, Javier; Geller, Ron; Sanjuan, Rafael; Pérez-Arévalo, José; Martínez-Moreno, Álvaro.
Trends Parasitol ; 37(1): 11-14, 2021 01.
Article in English | MEDLINE | ID: covidwho-867061

ABSTRACT

In recent months, the parasitology research community has been tasked with investigation of the influence of parasite coinfection on coronavirus disease 2019 (COVID-19) outcomes. Herein, we share our approach to analyze the effect of the trematode Fasciola hepatica as a modulator of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and of COVID-19 pathology.


Subject(s)
COVID-19/therapy , Coinfection , Fascioliasis , Helminth Proteins/therapeutic use , Animals , Antigenic Modulation , COVID-19/mortality , COVID-19/parasitology , COVID-19/pathology , Fasciola hepatica/metabolism , Humans , Immunity, Innate , Immunologic Factors/therapeutic use , Inflammation/prevention & control , Respiratory Distress Syndrome/prevention & control
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